looks like he needs a hair cut and put in a pot that isn't terra cotta. terra cotta dries out much more quickly than other types of pots, and for a plant that is used to a lot of water, that can be a problem.

also, when you cut the vines back, you can put any that have leaves on them in a glass of water and they will take root.

anytime you have a vine that goes over 6-8 inches without a leaf, that puts stress on the plant if it is used to having closer leaves.

also, another problem may be a change of light. when you repotted it, did you move it to another room?

Thanks for the thoughts. See how I'm caught between overwatering and to dry. I switched to the clay pot because I was hoping to help. The hair cut is a good idea, but scary. he's been in the same spot for a while and I have other pothos near by thats why I think the conditions are good. Is age really signifigant? I didn't realize that plants had a life span.

Becky- I don't know what PM is, but thanks.

IMO also, clay pots are ideal for pothos, as they like to dry out a bit, I've read to let dry 1" down(as Becky wrote), and read elsewhere to let dry even more than that, like the top third of the pot, which is what I do. Mine are in clay and thriving.

Hate to say it, but I think your pothos has just reached the end of it's life-span. Plants do have them. And, since you had this one so long and have others that are doing fine, you obviously know what you're doing in regards to pothos care. Don't grieve, if you make a new plant from it's cuttings it will have lived on!

Karamy

I did a big trim. You guys were right, He had one stem that was like 10 feet with no leaves. I did that around 2 weeks ago and the leaves look beter already. I think he's still fragile, but managing.

We're still in denial about the age thing. I changed vets when he said that about my dog. Turns out it was lymes disease!